“Rapid shifts in Europe’s drug market are creating new health and security risks” and are challenging the capacity to respond of both the EU institutions and relevant bodies. This warning comes from the European Union Drugs Agency (EUDA) in its “European Drug Report 2025: Trends and Developments” released today. Based on data from 29 countries (EU-27, Norway and Türkiye), this annual review highlights latest trends and emerging threats. Now in its 30th edition, the report “provides evidence to inform drug policy and practice”, the EUDA office in Lisbon explained. The report warns of risks to public health “posed by the availability and use of an increasingly diverse range of substances, often of high potency and purity”. Polysubstance use “remains a concern, complicating the delivery of effective prevention, treatment and harm reduction services”. European Commissioner for Internal Affairs Magnus Brunner said: “The illicit drug trade poses a severe threat to the health and security of our citizens. It promotes an environment of intimidation and corruption, jeopardizing the fabric of our communities, businesses and institutions”. “The fierce rivalry among criminal networks – he added – not only heightens gang violence and homicides but also increasingly involves the recruitment of minors into criminal activities”. “We are intensifying our efforts to dismantle these criminal organisations, disrupt drug trafficking operations, and address the troubling trend of youth recruitment”.